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Updated: Oct 1, 2025

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices
Published on: August 1, 2025
Small varices in chronic liver diseases.
Ying Zhu1, Hui Cheng1,2, Jianyong Chen3
1Department of Infectious Diseases, The First Affiliated Hospital of Dalian Medical University, Dalian.
Early detection and management of small gastroesophageal varices in chronic liver diseases are crucial. This review covers recent advances in diagnosing and treating these potentially life-threatening complications.
Area of Science:
- Hepatology
- Gastroenterology
- Medical Diagnostics
Background:
- Gastroesophageal varices are frequent complications of chronic liver diseases (CLDs) and portal hypertension.
- Small varices pose a risk of progression, leading to severe bleeding and mortality.
- Timely identification and management of small varices are essential for patient outcomes.
Purpose of the Study:
- To review recent advancements (last 5 years) in the diagnosis and management of small gastroesophageal varices in CLDs.
- To provide updated information for better understanding and appropriate clinical application in managing small varices.
Main Methods:
- Review of recent literature focusing on diagnostic and management strategies for small varices.
- Inclusion of improved endoscopic techniques (e.g., capsule endoscopy) and noninvasive methods (blood tests, imaging).
- Summarization of current approaches to the prevention and treatment of small varices.
Main Results:
- Diagnostic methods include enhanced endoscopic examinations and various noninvasive techniques like blood tests, ultrasound, CT, and MRI.
- Nonselective beta-blockers remain a key preventive strategy for small varices, despite ongoing debate.
- Recent progress in understanding variceal progression and management options has been identified.
Conclusions:
- Accurate diagnosis and proactive management of small varices are vital in CLD patients.
- A combination of advanced diagnostic tools and established medical therapies is recommended.
- Continued research and clinical vigilance are necessary for optimizing care for patients with small gastroesophageal varices.
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