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Application of Esmolol to Control Heart Rate and Artificial Intelligence Reconstruction Analysis for Rapid

Chenfeng Ni1, Lei Pei1, Miaoping Zhou1

  • 1Department of Radiology, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, Zhejiang 324000, China.

Journal of Healthcare Engineering
|March 8, 2022
PubMed

Insights

Esmolol effectively reduces heart rate for emergency coronary CT angiography (CTA) in patients with high heart rates or inability to hold their breath. This rapid method, combined with AI analysis, ensures effective diagnosis without compromising image quality.

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Pharmacology

Background:

  • Coronary computed tomography angiography (CTA) is crucial for emergency patients.
  • High heart rates and inability to hold breath impede CTA quality in critically ill patients.

Purpose of the Study:

  • To evaluate a rapid and effective method for coronary CTA in emergency settings.
  • To assess the utility of esmolol for heart rate reduction and AI for image analysis.

Main Methods:

  • Intravenous esmolol was administered for rapid heart rate reduction under ECG monitoring.
  • Coronary CTA was performed using a 640-slice high-speed CT scanner.
  • Artificial intelligence software was used for subsequent reconstruction analysis.

Main Results:

  • The diagnostic rate for coronary artery segments with excellent/good CTA images was 95.4% in the esmolol group versus 91.1% in the control group.
  • Esmolol achieved rapid heart rate reduction with a short half-life and minimal side effects.
  • No significant statistical difference was found between the groups (P > 0.05).

Conclusions:

  • Esmolol injection is a safe and effective method for rapid heart rate control in patients undergoing coronary CTA.
  • The combination of esmolol and AI-powered analysis offers a novel approach for efficient coronary CTA in emergency patients.
  • This method eliminates the need for breath-holding or extensive preoperative preparation.
Abstract

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