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Published on: February 9, 2011
Eikenella corrodens infections in children
Abstract:
Techniques for obtaining, transporting, and culturing bacteriologic specimens have improved in recent years. The laboratory is now identifying rare fastidious organisms in surgical infections, which were previously unknown to clinicians. One of these organisms, Eikenella corrodens, was found in 28 children over 5 years. It was most commonly found in patients with perforated appendices or in wounds with oral contamination. Eikenella most often occurs in multibacterial infections but has also been grown in pure culture. When this bacteria is found in a patient with a serious surgical infection the wound must be widely opened and debrided of necrotic tissue. Prolonged antibiotic therapy based on culture and sensitivity is necessary to prevent prolonged or recurrent infection.
Insights
Recent advancements allow identification of rare bacteria like Eikenella corrodens in surgical infections. This organism, often found in oral contamination, requires surgical debridement and prolonged antibiotics for treatment.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Surgical Infections
Background:
- Improved bacteriologic specimen techniques enhance pathogen identification.
- Rare fastidious organisms are increasingly detected in surgical infections.
- Eikenella corrodens is an emerging pathogen in pediatric surgical cases.
Purpose of the Study:
- To report the incidence and clinical significance of Eikenella corrodens in pediatric surgical infections.
- To highlight the association of Eikenella corrodens with specific types of surgical wounds.
- To outline appropriate management strategies for Eikenella corrodens infections.
Main Methods:
- Retrospective analysis of pediatric surgical cases over a 5-year period.
- Identification of Eikenella corrodens through bacteriologic culturing.
- Clinical data review for patient demographics, infection sources, and treatment outcomes.
Main Results:
- Eikenella corrodens was identified in 28 pediatric patients over 5 years.
- The organism was most frequently isolated from perforated appendices and orally contaminated wounds.
- Eikenella corrodens was often part of polymicrobial infections but also found in pure culture.
Conclusions:
- Eikenella corrodens is an important pathogen in pediatric surgical site infections, particularly those involving oral contamination.
- Effective management necessitates prompt surgical intervention, including debridement of necrotic tissue.
- Extended antibiotic therapy guided by culture and sensitivity testing is crucial for successful treatment and prevention of recurrence.
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