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Related Concept Videos

Nose and Nasal Cavity01:24

Nose and Nasal Cavity

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The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
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The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
Nose and nasal cavity
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The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
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Related Experiment Video

Updated: Oct 1, 2025

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
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[Sinonasal cancers].

François-Régis Ferrand1, Juliette Thariat2, Benjamin Verillaud3

  • 1Institut de recherche biomédicale des armées, Brétigny-sur-Orge, France, département de carcinologie cervicofaciale, institut Gustave-Roussy, Villejuif, France.

La Revue Du Praticien
|March 8, 2022
PubMed
Summary
This summary is machine-generated.

Sinonasal cancers (SNC) are rare head and neck tumors. Increased physician awareness of SNC diagnosis, treatment, and functional outcomes is crucial for optimal patient care and monitoring.

Keywords:
Paranasal Sinus Neoplasms

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Area of Science:

  • Oncology
  • Head and Neck Surgery
  • Rare Tumors

Background:

  • Sinonasal cancers (SNC) are rare tumors within the head and neck cancer spectrum.
  • SNC encompass diverse histological subtypes, complicating diagnosis and management.
  • Physicians require enhanced awareness of diagnostic and therapeutic strategies for SNC.

Purpose of the Study:

  • To increase physician awareness of sinonasal cancer diagnosis and treatment.
  • To highlight functional consequences and long-term monitoring of SNC patients.
  • To review current and emerging therapeutic options for SNC.

Main Methods:

  • Review of histological entities within SNC.
  • Discussion of advanced therapeutic modalities including endoscopic surgery, radiotherapy, and systemic treatments.
  • Emphasis on the role of expert networks (REFCOR) and patient support associations (CORASSO).

Main Results:

  • SNC require specialized diagnostic and therapeutic approaches due to their rarity and heterogeneity.
  • New treatments like endoscopic surgery and advanced radiotherapy offer improved outcomes.
  • Multidisciplinary collaboration through networks and associations is vital for comprehensive patient management.

Conclusions:

  • Optimal management of sinonasal cancers necessitates heightened physician awareness and specialized care.
  • Integration of novel surgical, radiological, and systemic therapies improves patient outcomes.
  • Expert networks and patient support systems are essential for holistic SNC care.