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[Factors associated with intrahospital mortality in older patients with COVID-19 in Belgium : The COVID-AgeBru study]

E Garcia1, D Sanchez-Rodriguez1,2,3,4, S Levy5

  • 1Faculté de Médecine, ULB, Bruxelles, Belgique.

Revue Medicale De Liege
|March 8, 2022
PubMed

Insights

Older COVID-19 patients in Belgium face higher mortality risks with increasing age, type 2 diabetes, and acute respiratory distress syndrome (ARDS). These factors significantly impact intrahospital survival rates for elderly individuals. Keywords: COVID-19 mortality, elderly patients, Belgium, type 2 diabetes, ARDS.

Area of Science:

  • Gerontology
  • Infectious Diseases
  • Public Health

Background:

  • COVID-19 significantly impacts older populations globally.
  • Assessing intrahospital mortality risk factors in elderly COVID-19 patients is crucial for targeted interventions.
  • Belgian healthcare data provides a specific context for understanding these risks.

Purpose of the Study:

  • To determine the association between demographic, clinical factors, and intrahospital mortality in older COVID-19 patients in Belgium.
  • To identify specific risk factors contributing to mortality in this vulnerable population.

Main Methods:

  • A descriptive, retrospective study was conducted at Brugmann University Hospital, Brussels.
  • Inclusion criteria: patients aged ≥70 years admitted with confirmed COVID-19.
  • Data collected included demographics, comorbidities, and comprehensive geriatric assessment; logistic regression analysis was performed.

Main Results:

  • 160 elderly patients (mean age 82.7 years) were included; 42% died during hospitalization.
  • Adjusted logistic regression revealed significant associations between mortality and increasing age (OR=1.09), type 2 diabetes (OR=2.75), and acute respiratory distress syndrome (ARDS) (OR=8.67).

Conclusions:

  • Increasing age, type 2 diabetes, and ARDS are positively associated with higher intrahospital mortality in older COVID-19 patients in Belgium.
  • Further research is needed to explore the prognostic value of comprehensive geriatric assessment in this cohort.
Abstract

Keywords:
AgeBelgiumComorbidityHospitalMortalityRisk factor19COVID

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