Related Experiment Video
Updated: Oct 1, 2025

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
Discussion on the Structural Modification and Anti-tumor Activity of Flavonoids
Zhu-Gui Zhou1, Dong-Dong Li2, Ying Chen3
1Agro-food Science and Technology Research Institute, Guangxi Academy of Agricultural Sciences, Guangxi Key Laboratory of Fruits and Vegetables Storage-processing Technology, Nanning, 530007, China.
Abstract:
Flavonoids are secondary metabolites of plants. In general,most flavonoids are combined with glucosides and have extremely complex molecular structures. In nature, these flavonoids have a variety of biological activities, such as anti-oxidation,anti-virus, anti-tumor, scavenging free radicals, etc.; however,due to poor solubility and stability of flavonoids,their bioavailability is limited. The drug design method is used to modify the structure of flavonoids to give them special properties. At present, flavonoids have shown broad application prospects in treating tumors, inhibiting proliferation, migration, invasion, angiogenesis, and multi-drug resistance of tumors and have become a research hotspot.
Related Concept Videos
Cancer Prevention
Some...
Drugs that Stabilize Microtubules
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Drugs that Destabilize Microtubules
Inhibition of Cdk Activity
Targeted Cancer Therapies
There are several types of targeted therapies against...

