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[Aplasia cutis congenita. Report of 2 cases]
Insights
Two rare pediatric cases of aplasia cutis congenita were documented in Peru. This study details their clinical presentation, associated defects, and management, highlighting the condition
Area of Science:
- Dermatology
- Pediatrics
- Medical Genetics
Background:
- Aplasia cutis congenita (ACC) is a rare congenital skin defect.
- Documenting rare disease presentations is crucial for understanding global incidence and regional variations.
Observation:
- Two pediatric cases of ACC were observed at a regional hospital in Trujillo, Peru.
- Case 1 presented with an ulcer defect on the right lower limb.
- Case 2 exhibited a midline scalp lesion associated with other congenital malformations.
Findings:
- Detailed clinical and histological characteristics of both ACC cases are presented.
- Associated congenital anomalies and potential etiopathogenic mechanisms are discussed.
- The rarity of these presentations, particularly in Peru, is emphasized.
Implications:
- This report contributes to the limited global data on aplasia cutis congenita.
- It underscores the importance of recognizing and managing ACC in pediatric populations.
- Further research into the etiology and treatment of ACC is warranted.
Abstract:
In 1983, we had two cases of pediatric patients, which were observed in the Regional Hospital "Victor Lazarte Echegaray" of the Peruvian Institute of Social Security in Trujillo, these cases correspond to the syndrome of aplasia cutis congenita. In the first case, the defect was localized as a of ulcer in the right inferior member, which was affected from the third part distal of the thigh to the back part of the foot. In the second one, the lesion was in the middle line of the hairy skin, and it had the particularity of being associate to others congenital malformations. These cases are mentioned because of their rarity of presentation at a world level as well as their unknown occurrence in our country. Then we comment the clinic, histological characteristics, associate congenital defects, possible etiopathogenic mechanisms, differential diagnostic and its evolution and treatment.