Well-differentiated mesenteric liposarcoma: report of two cases

Area of Science:

• Oncology
• Surgical Oncology
• Gastrointestinal Oncology

Background:

• Liposarcoma is a rare malignancy with challenging diagnosis and treatment due to nonspecific symptoms and lack of established therapies.
• Surgical resection is the primary treatment for localized liposarcoma, but management can be complex.
• Primary mesenteric liposarcoma is exceptionally rare, posing unique clinical and surgical challenges.

Observation:

• This report details two distinct cases of primary mesenteric liposarcoma.
• The first case presented with significant symptoms of small bowel obstruction, including abdominal distention and severe pain.
• The second case was an incidental finding during surgery for an incisional hernia.

Findings:

• Histopathological examination confirmed well-differentiated liposarcoma in both patients.
• Both patients successfully underwent complete surgical resection of the mesenteric tumors.
• The diverse clinical presentations underscore the varied manifestations of mesenteric liposarcoma.

Implications:

• These cases demonstrate that surgical resection is a feasible and effective treatment for primary mesenteric liposarcoma.
• Early diagnosis and prompt surgical intervention are crucial for favorable outcomes in liposarcoma management.
• Further research into the optimal diagnostic and therapeutic strategies for rare liposarcomas is warranted.