Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Differentiation of Common Myeloid Progenitor Cells

Differentiation of Common Myeloid Progenitor Cells

Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...

Abnormal Proliferation

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The critical role of standards for AI in digital pathology: Digital Pathology Association Concept Paper.

Journal of pathology informatics·2026

Same author

NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.

Frontiers in immunology·2025

Same author

Knowledge, attitude and psychological impact of cyberbullying among adolescents. A cross-sectional study.

Journal of family medicine and primary care·2024

Same author

Unveiling the Tempest: Dermal Plasmacytoid Dendritic Cell Proliferation as the Harbinger of Acute Myeloid Leukemia.

The American Journal of dermatopathology·2024

Same author

Detailed Analysis of Simultaneous Renal and Liver Allografts in the Presence of DSA.

Transplantation direct·2023

Same author

Intraventricular neurocysticercosis causing obstructing hydrocephalus.

Proceedings (Baylor University. Medical Center)·2022

Same journal

Evaluating the rising incidence of infant botulism and the heterogeneous distribution of cases in Texas in the wake of the November 2025 outbreak.

Proceedings (Baylor University. Medical Center)·2026

Same journal

Young-onset signet ring cell colorectal adenocarcinoma: demographics, clinicopathological profile, and survival analysis.

Proceedings (Baylor University. Medical Center)·2026

Same journal

Supporting patient understanding of cervical and ovarian cancer: how well does AI perform?

Proceedings (Baylor University. Medical Center)·2026

Same journal

Nationwide analysis of adult nongonococcal septic knee arthritis hospitalizations from 2016 to 2022.

Proceedings (Baylor University. Medical Center)·2026

Same journal

Ferrier and Horsley in America, 1888: cerebral localization and neurosurgery.

Proceedings (Baylor University. Medical Center)·2026

Same journal

Anesthetic management of a high-risk cesarean delivery in a patient with multivessel Takayasu arteritis.

Proceedings (Baylor University. Medical Center)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Oct 1, 2025

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts

Published on: June 13, 2019

An unusual myeloid sarcoma.

John R Krause¹, Samreen Fathima¹, Rory Richard Mayer²

¹Section of Hematopathology, Department of Pathology, Baylor University Medical Center, Dallas, Texas.

Proceedings (Baylor University. Medical Center)

|March 9, 2022

Summary

This summary is machine-generated.

This case report details a rare instance of de novo promyelocytic granulocytic sarcoma in a young man, presenting as a paraspinal tumor mass. This highlights the diverse and uncommon presentations of myeloid sarcoma.

Keywords:

Granulocytic sarcoma myeloid sarcoma promyelocytic leukemia

More Related Videos

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas

Published on: September 13, 2019

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

Related Experiment Videos

Last Updated: Oct 1, 2025

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts

Published on: June 13, 2019

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas

Published on: September 13, 2019

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

Area of Science:

Hematology
Oncology
Pathology

Background:

Myeloid sarcoma is characterized by extramedullary tumor masses of immature myeloid or monocytic cells.
Granulocytic sarcoma, a subtype, is uncommon, with de novo promyelocytic forms being exceptionally rare.

Observation:

A young male patient presented with a paraspinal mass.
Diagnostic evaluation revealed the mass to be myeloid sarcoma of promyelocytic origin.

Findings:

The case confirmed a de novo promyelocytic granulocytic sarcoma.
The tumor's location was identified as a paraspinal site.

Implications:

This case expands the understanding of myeloid sarcoma's rare presentations.
Highlights the importance of considering granulocytic sarcoma in differential diagnoses for extramedullary masses.