Morphological and immunohistochemical study in Hodgkin's disease
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Neoplasma
|January 1, 1986
Abstract:
Histogenesis of different microscopical types of Hodgkin's disease was investigated in a series of 19 patients by morphological and immunohistochemical methods. The main changes affecting the lymphatic system occur in perivascular areas, which contain a great amount of thymic factor. The Hodgkin's and Reed-Sternberg cells appear to arise from the perivascular mesenchyme and some of them have cross-striated cytoplasm.