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Albumin Kinetics in Sepsis and COVID-19
Suhail Sarwar Siddiqui1, Nilanchal Chakraborty2, Syed Nabeel Muzaffar1
1Department of Critical Care Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.
Abstract:
Hypoalbuminemia has been associated with poor outcome in critically ill population including sepsis and COVID-19. The observational study by Su et al showed a favorable albumin kinetics, with an initial downwards trend followed by recovery back to the predicted albumin levels, in survivors of COVID-19 and sepsis-induced acute respiratory distress syndrome (ARDS). However, nonsurvivors in COVID-19 group did not have an upwards recovery slope, while those in sepsis group did not follow any sort of albumin kinetics. Thus, authors concluded that the pattern of albumin kinetics may be predictive of outcome in COVID-19 and sepsis-induced ARDS. Here, we would like to highlight a few more points in this letter.
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