The ECOTOXicology Knowledgebase: A Curated Database of Ecologically Relevant Toxicity Tests to Support Environmental...

Area of Science:

• Environmental toxicology
• Ecotoxicology
• Chemical safety assessment

Background:

• Growing chemical introduction necessitates comprehensive toxicity data.
• Regulatory mandates require robust safety assessments for chemicals.
• The ECOTOXicology Knowledgebase (ECOTOX) has been a key resource since the 1980s.

Purpose of the Study:

• To provide an overview of the ECOTOXicology Knowledgebase (ECOTOX).
• To detail literature review and data curation processes.
• To discuss recent updates enhancing data accessibility and reusability for environmental chemical management and research.

Main Methods:

• Systematic and transparent literature review procedures.
• Extraction of toxicity data using controlled vocabularies.
• Quarterly updates with newly extracted toxicity data.

Main Results:

• ECOTOX Version 5 contains data for over 12,000 chemicals and ecological species.
• Over one million test results from more than 50,000 references are available.
• Redesigned user interface with enhanced queries, visualizations, and export options.

Conclusions:

• ECOTOX is a reliable source of curated ecological toxicity data.
• Recent updates improve data accessibility, reusability, and interoperability.
• The database supports chemical assessment, management, and research through state-of-the-art practices.