ICTV Virus Taxonomy Profile: Adenoviridae 2022

Area of Science:

• Virology
• Microbiology
• Animal Health

Background:

• Adenoviruses are non-enveloped viruses with double-stranded DNA (dsDNA) genomes.
• These viruses possess medium-sized icosahedral capsids and infect vertebrates across diverse species.
• The Adenoviridae family encompasses six genera, with varying prevalence in different animal groups.

Purpose of the Study:

• To provide a comprehensive summary of the International Committee on Taxonomy of Viruses (ICTV) report on the Adenoviridae family.
• To detail the classification, characteristics, and host range of adenoviruses.
• To outline the spectrum of disease outcomes associated with adenovirus infections.

Main Methods:

• Review and synthesis of the official ICTV report on Adenoviridae.
• Compilation of data on viral structure, genome, and classification.
• Summary of known hosts and associated pathologies.

Main Results:

• Adenoviridae viruses are characterized by non-enveloped icosahedral capsids and linear dsDNA genomes (25-48 kb).
• Adenoviruses infect a wide range of vertebrates, from fish to humans.
• The family is taxonomically divided into six genera, each with specific animal group associations.

Conclusions:

• Adenovirus infections present a variable clinical spectrum, ranging from subclinical to lethal.
• This summary serves as an accessible overview of the current taxonomic understanding of Adenoviridae.
• The findings are based on the official ICTV classification and are publicly available.