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Updated: Oct 1, 2025

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Oral Biofilm Formation on Different Materials for Dental Implants
Published on: June 24, 2018
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Emerging titanium surface modifications: The war against polymicrobial infections on dental implants
Valentim A R Barão1, Raphael C Costa1, Jamil A Shibli2
1Department of Prosthodontics and Periodontology, Piracicaba Dental School, University of Campinas(UNICAMP), Piracicaba, Brazil.
Brazilian Dental Journal
|March 9, 2022
Summary
Dental implant surfaces attract microbes, leading to biofilm formation and peri-implantitis, a major cause of implant failure. Surface modifications are explored to combat microbial accumulation and prevent infections.
Area of Science:
- Biomaterials Science
- Microbiology
- Periodontology
Background:
- Titanium (Ti) dental implants are a successful treatment for edentulism but are prone to microbial adhesion.
- Biofilm formation on implant surfaces causes peri-implant mucositis and peri-implantitis, leading to implant failure.
Purpose of the Study:
- To review current evidence on dental implant biofilm accumulation and pathogenesis of implant-related infections.
- To discuss surface modifications for anti-biofilm properties to control peri-implantitis.
Main Methods:
- Critical review of existing literature on dental implant biofilms.
- Analysis of factors contributing to microbial accumulation and pathogenicity.
- Evaluation of surface modification strategies for anti-biofilm properties.
Main Results:
- Biofilm formation is driven by factors like matrix production, carbohydrate availability, and cross-kingdom interactions.
- Implant topography and biofilm characteristics (organization, resistance) hinder microbial control.
- No consensus exists on optimal protocols for microbial control and peri-implant disease treatment.
Conclusions:
- Understanding biofilm pathogenesis is crucial for developing effective peri-implantitis treatments.
- Surface modifications offer promising strategies to reduce microbial load and prevent implant-related infections.
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