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Updated: Oct 1, 2025

Traumatic Peripheral Nerve Injury in Mice
Published on: March 25, 2022
Ballistic peripheral nerve injuries: basic concepts, controversies, and proposal for a management strategy
Laurent Mathieu1,2,3, Melody Goncalves4,5, James Charles Murison4,5
1Department of Orthopedic, Trauma and Reconstructive Surgery, Percy Military Hospital, 101 avenue Henri Barbusse, 92140, Clamart, France. laurent_tom2@yahoo.fr.
Ballistic peripheral nerve injuries require prompt surgical evaluation and repair. A standardized strategy, including early exploration and tailored techniques like suturing, grafting, or transfers, improves outcomes for trauma patients.
Area of Science:
- Trauma Surgery
- Neurology
- Ballistics
Background:
- Ballistic peripheral nerve injuries cause significant morbidity, including functional loss and chronic pain.
- Surgical management presents challenges due to injury complexity and timing.
Purpose of the Study:
- To present basic ballistic concepts relevant to nerve lesions.
- To review current controversies in surgical management.
- To propose a standardized management strategy for ballistic nerve injuries.
Main Methods:
- Literature review and anecdotal evidence synthesis.
- Explanation of missile nerve lesion types using Sunderland classification.
- Discussion of surgical timing and neurolysis relevance.
Main Results:
- Early nerve exploration is crucial for diagnosis in acute and sub-acute periods.
- Direct suturing with joint flexion is recommended for limited defects.
- Nerve grafting and transfers are indicated for large or proximal defects.
Conclusions:
- A standardized approach to ballistic nerve injuries improves surgical decision-making.
- Optimal timing for nerve repair depends on defect characteristics and infection risk.
- Tailored surgical interventions, including tendon transfers, can aid functional recovery.
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