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Epstein-Barr virus BNRF1 destabilizes SMC5/6 cohesin complexes to evade its restriction of replication compartments

Stephanie Pei Tung Yiu1, Rui Guo2, Cassie Zerbe3

  • 1Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA; Harvard Graduate Program in Virology, Boston, MA 02115, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA.

Cell Reports
|March 9, 2022
PubMed

Keywords:
R-loopantiviral defensecalpainherpesvirusinnate immunitylytic reactivationstructural maintenance of chromosomestegumentubiquitin proteasomeviral replication compartment

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