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Topical Fluoride Effectiveness in High Caries Risk Adults.

M M Jurasic1,2, G Gibson3, M B Orner4

  • 1General Dentistry and Health Policy and Health Services Research, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA.

Journal of Dental Research
|March 10, 2022
PubMed
Summary
This summary is machine-generated.

Topical fluoride treatments like varnishes and gels/rinses significantly reduce the need for new dental restorations and extractions in high-caries-risk adults. Multiple applications offer greater protection against new caries.

Keywords:
big datacaries preventionclinical outcomescomparative effectiveness researchelectronic dental recordshealth services research

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Area of Science:

  • Dental Public Health
  • Cariology
  • Preventive Dentistry

Background:

  • High caries risk adults require effective preventive strategies to reduce restorative treatment and extractions.
  • Topical fluoride applications are a cornerstone of caries prevention, but optimal types, combinations, and intensities require further elucidation.

Purpose of the Study:

  • To determine the effectiveness of different types, combinations, and intensities of topical fluorides in preventing new caries-related restorations and extractions.
  • To analyze longitudinal data from high caries risk adults within the US Department of Veterans Affairs healthcare system.

Main Methods:

  • Retrospective analysis of longitudinal data from electronic dental, medical, and pharmacy records (October 1, 2008–June 30, 2018).
  • Inclusion criteria: eligible for comprehensive care, high caries risk (≥2 restorations/365 days), and 3 years of follow-up.
  • Multivariable logistic regression models controlled for demographic, clinical, and treatment variables to estimate odds of caries-related treatment.

Main Results:

  • Veterans receiving fluoride varnish or gel/rinse interventions showed approximately 29% decreased odds of caries-related treatment compared to no fluoride (AORs 0.72 and 0.71, respectively).
  • Combined varnish and gel/rinse interventions did not demonstrate statistically superior outcomes compared to individual interventions.
  • A dose-response effect was observed, with two or more applications of varnish or gel/rinse being more effective than a single application.

Conclusions:

  • Topical fluoride varnishes and gel/rinses are effective in reducing caries-related treatment in high caries risk adults.
  • Multiple applications of topical fluorides demonstrate a dose-response relationship, enhancing preventive efficacy.
  • These findings support the use of regular topical fluoride applications as a key strategy in managing caries risk.