Related Experiment Video
Updated: Oct 1, 2025

Two Methods for Establishing Primary Human Endometrial Stromal Cells from Hysterectomy Specimens
Published on: May 23, 2014
Endometrium at Menopause: The Pathologist's View
Meenakshi Swain1, Aditya D Kulkarni1
1Department of Histopathology, Apollo Health City, Hyderabad, Telangana, India.
Abstract:
Endometrium at menopause is inactive and free of cyclical changes that are characteristics of the reproductive age. At the same time, menopausal endometrium is subject to a variety of disease processes, the most sinister of which are the endometrial malignancies. In the present pictorial review, we briefly discuss the various morphologic patterns of diseases affecting the menopausal endometrium. With an aim to provide insights from the pathologists' point of view, multiple pictures for each of the disorders are shared. We highlight the finer points a pathologist looks for, to ensure proper treatment and welfare of postmenopausal women.
More Related Videos
07:20Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
Published on: December 21, 2012
08:07Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
Published on: April 5, 2024
Related Concept Videos
Menopause
The Menstrual Cycle
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a...
Menses Phase
When fertilization does not occur, the corpus luteum deteriorates, causing a significant drop in the levels of estrogen and progesterone in the body. This hormonal decrease triggers the release of prostaglandins, which cause the uterine...
Proliferative Phase
Notably, the stratum basale, the basal layer of the endometrium, including the basal parts of the uterine glands, remains unaffected by menstruation. Stem cells in this layer undergo mitosis, regenerating the stratum functionalis and thickening the...
Oogenesis
Hormonal Regulation of the Menstrual Cycle
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...