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Updated: Oct 1, 2025

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide
Published on: January 15, 2017
Medication adherence early after stroke: using the Perceptions and Practicalities Framework to explore stroke
Josephine Gibson1, Jacqueline Coupe2, Caroline Watkins3
1Reader in Health Services Research, School of Nursing, University of Central Lancashire, Preston, UK.
Background:
Secondary prevention medication after stroke reduces risk of recurrence, but adherence is often poor. Stroke survivors', carers' and nurses' perspectives of early post-stroke medication adherence are unexplored.
Aim:
The aim of this study was to explore stroke survivors', carers' and nurses' views and experiences about adhering to medication early after post-stroke hospital discharge.
Methods:
Qualitative individual and group interviews, utilising the Perceptions and Practicalities Framework, were employed. Nine people <2 months post-stroke, three carers and 15 nurses from one UK stroke unit participated. Interviews were digitally recorded, transcribed and thematically analysed.
Results:
There were four main themes with two sub-themes. (1) Perceptions of medication taking after stroke. Factors affecting adherence included depression, imperceptible benefits and concerns about adverse effects. (2) Perceptions about those at higher risk of poor medication adherence. Nurses suggested that poor adherence might be more likely in those living alone or with previous non-adherence. (3) Practicalities of taking medication early after stroke; these included post-stroke disabilities, cognition, polypharmacy and lack of information. (4a) Practicalities of addressing poor medication adherence during the hospital stay. Solutions included multidisciplinary co-ordination, but nurses and stroke survivors described suboptimal use of opportunities to promote adherence. (4b) Practicalities of addressing poor medication adherence post-discharge. Solutions included modifications and support from carers, but stroke survivors reported difficulties in evolving systems for taking medications.
Conclusions:
Stroke survivors and informal carers lack knowledge and support needed to manage medication early after discharge. Nurses' opportunities to promote medication adherence are under-exploited. Medication adherence strategies to support stroke survivors early after discharge are needed.
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