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Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

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Published on: August 13, 2019

Surgical guides for guided bone augmentation: An in vitro study.

Mihai Tarce^1,2, Joe Merheb^1,2, Marc Meeus^1,2

¹Periodontology and Oral Microbiology, Department of Oral Health Sciences, KU Leuven, Leuven, Belgium.

Clinical Oral Implants Research

|March 10, 2022

Summary

This study validates a novel surgical guide for bone augmentation, showing it significantly improves graft accuracy and reduces material waste in horizontal alveolar defects. While surgical time increased, the guided method offers better control over graft placement.

Keywords:

in vitro bone augmentation dental implant particulate graft surgical guide

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Last Updated: Sep 30, 2025

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Published on: August 13, 2019

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Published on: January 28, 2020

Area of Science:

Oral and Maxillofacial Surgery
Dental Implantology
Regenerative Dentistry

Background:

Horizontal alveolar bone defects pose challenges for dental implant placement.
Accurate bone augmentation is crucial for successful implant outcomes.
Conventional bone grafting techniques can lack precision in shape and volume control.

Purpose of the Study:

To validate the in vitro accuracy of a novel surgical guide for horizontal alveolar bone augmentation.
To compare the precision of a guided versus a conventional bone grafting protocol.
To assess graft volume, accuracy, density, and surgical time.

Main Methods:

Cone-beam computed tomography scans of alveolar defects were 3D printed.
Surgeons performed bone augmentation on 3D models using conventional and guided protocols.
Graft accuracy, volume, density, and surgical time were analyzed and compared.

Main Results:

The guided protocol significantly reduced graft volume outside the planned area (19.6% vs. 36.8%).
Guided surgery improved accuracy at multiple measurement points, minimizing overfill.
A 1mm increase in graft thickness coronally was observed with the guided protocol; surgical time increased by 2m 26s.

Conclusions:

The novel surgical guide technique improves the accuracy of bone graft shape in vitro.
The guided approach enhances material compaction in the coronal graft portion.
This method effectively reduces the placement of graft material outside the intended surgical volume.