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Reducing Metabolic Syndrome through a Group Educational Intervention Program in Adults with Obesity: IGOBE Program
Cristina Tejera1,2, Cristina Porca1,2, Gemma Rodriguez-Carnero2,3
1Division of Endocrinology and Nutrition, Complejo Hospitalario Universitario de Ferrol (CHUF/ SERGAS), 15405 Ferrol, Spain.
Nutrients
|March 10, 2022
Summary
An intensive lifestyle program significantly reduced metabolic syndrome (MetS) prevalence in obese adults by 13.4% over 12 months. This healthy lifestyle intervention proved more effective than usual care in managing MetS risk factors.
Area of Science:
- Obesity and metabolic health research
- Clinical intervention studies
- Cardiovascular disease and diabetes prevention
Background:
- Metabolic syndrome (MetS) is a cluster of conditions that increase the risk of cardiovascular disease, type 2 diabetes, and cancer.
- Obesity is strongly linked to a higher prevalence of MetS, yet effective interventions remain under investigation.
- Intensive lifestyle programs show potential for managing MetS in obese populations.
Purpose of the Study:
- To evaluate the effectiveness of an intensive lifestyle program (IGOBE) in reducing MetS prevalence among adults with obesity.
- To compare the impact of the IGOBE program versus usual care on MetS features.
- To assess long-term (12-month) outcomes of lifestyle intervention in obese individuals with MetS.
Main Methods:
- A prospective, randomized, real-life study involving 456 adults with obesity.
- Participants were assigned to either a control group (usual care) or an intervention group (IGOBE program with 6 weekly sessions).
- Data on anthropometrics, body composition, medications, and MetS features were collected pre- and post-intervention, analyzed using completer's analysis.
Main Results:
- The intervention group (IG) demonstrated a 13.4% relative reduction in MetS prevalence at 12 months, compared to 2.1% in the control group (p < 0.001).
- Significant improvements were observed in four out of five MetS features in the IG.
- The IGOBE program led to a significant reduction in MetS prevalence and better control of associated risk factors compared to standard care.
Conclusions:
- The IGOBE intensive lifestyle program is effective in significantly reducing MetS prevalence in adults with obesity.
- This intervention offers a superior approach to standard care for managing metabolic syndrome and its components.
- Lifestyle modification programs are crucial for mitigating the health risks associated with obesity and MetS.
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