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Homeostasis. VII. A conspectus.

E A Murphy, R E Pyeritz

    American Journal of Medical Genetics
    |August 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    This review explores physiological homeostasis, its characteristics, and properties, laying groundwork for genetic analysis. It uses examples like type II diabetes mellitus to illustrate concepts.

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    Area of Science:

    • Physiology
    • Genetics
    • Endocrinology

    Background:

    • Physiological homeostasis is crucial for maintaining stable internal body conditions.
    • Understanding homeostasis is essential for studying diseases like type II diabetes mellitus.

    Purpose of the Study:

    • To broadly review the characteristics and properties of physiological homeostasis.
    • To provide a foundation for definitive genetic analysis of homeostatic mechanisms.
    • To illustrate homeostatic principles using common physiological and pathophysiological examples.

    Main Methods:

    • Literature review of physiological homeostasis.
    • Analysis of common physiological and pathophysiological examples.
    • Focus on type II diabetes mellitus as a case study.

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    Main Results:

    • A comprehensive overview of physiological homeostasis characteristics and properties.
    • Identification of key areas for future genetic research in homeostasis.
    • Illustrative examples connecting homeostasis to type II diabetes mellitus.

    Conclusions:

    • The review provides a framework for understanding homeostasis for genetic research.
    • Homeostatic dysregulation is implicated in type II diabetes mellitus.
    • Further genetic investigation into homeostasis is warranted.