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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
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Use of CIED Generated Heart Failure Risk Score (HFRS) Alerts in an Integrated, Multi-Disciplinary Approach to HF
Daniel Garner1, Lindsay Lunt1, Wing Leung1
1Liverpool Heart and Chest Hospital, Thomas Drive, Liverpool L14 3PE, UK.
Sensors (Basel, Switzerland)
|March 10, 2022
Summary
Integrated heart failure management using CIED-generated alerts identifies high-risk patients, enabling timely intervention and holistic care for improved outcomes.
Area of Science:
- Cardiology
- Medical Technology
- Health Services Research
Background:
- Cardiovascular Implantable Electronic Devices (CIEDs) can generate alerts for heart failure (HF).
- Integrated, multidisciplinary approaches are crucial for effective HF management.
- The Heart Failure Risk Score (HFRS) alert system requires evaluation within a clinical pathway.
Purpose of the Study:
- To assess the utility of CIED-generated HFRS alerts in an integrated HF management strategy.
- To evaluate healthcare utilization (HCU) and mortality in patients receiving HFRS alerts.
- To gather feedback from healthcare teams on the integrated management pathway.
Main Methods:
- Prospective, single-center outcome study of patients with HFRS-enabled CIEDs generating high-risk alerts.
- Management within an integrated HF pathway with alert sharing and prompt intervention.
- Collection of HCU and mortality data, with validated team feedback questionnaires.
Main Results:
- 188 patients generated 367 high-risk HFRS alerts; 23% had >3 alerts.
- 39% of patients were hospitalized within 4-6 weeks of an alert; 13% for decompensated HF.
- Three or more alerts significantly increased HF hospitalization risk (HR 2.5, p=0.03); 18% mortality.
Conclusions:
- High-risk HFRS alerts identify comorbid patients with significant HCU.
- An integrated approach facilitates timely risk stratification and intervention for these complex patients.
- This pathway allows for holistic management beyond HF alone.
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