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Structural basis for the activity and regulation of human α-ketoglutarate dehydrogenase revealed by Cryo-EM

Youhuan Zhong1, Yuanzhu Gao2, Dejian Zhou3

  • 1Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, PR China.

Biochemical and Biophysical Research Communications
|March 10, 2022
PubMed

Keywords:
Enzyme mechanismMitochondriaSingle-particle cryo-electron microscopyThiamine diphosphateα-ketoglutarate dehydrogenase

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