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Structure-Function Analysis of MP-3 Microperimetry versus Octopus Perimetry in Central Glaucomatous Visual Field
Stefan Georgiev1, Stefan Palkovits2, Nino Hirnschall2
1Department of Ophthalmology, Hanusch Hospital, Vienna Institute for Research in Ocular Surgery, Vienna, Austria, s.georgiev@viros.at.
Ophthalmic Research
|March 10, 2022
Summary
Microperimetry and Octopus perimetry show similar structure-function relationships in primary open-angle glaucoma (POAG) patients. Further longitudinal studies are needed to evaluate fundus-tracking for glaucoma assessment.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Visual Neuroscience
Background:
- Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness.
- Assessing the structure-function relationship is crucial for monitoring glaucoma progression.
- Central visual field defects are common in POAG patients.
Purpose of the Study:
- To compare the structure-function relationship between microperimetry and Octopus perimetry.
- To evaluate these relationships in POAG patients with central visual field defects.
Main Methods:
- Forty eyes of 24 POAG patients were analyzed.
- Circumpapillary retinal nerve fiber layer (cpRNFL) thickness measured by SD-OCT was correlated with visual field data from microperimetry and Octopus perimetry.
- Structure-function relationships were assessed using linear and segmented regression analyses.
Main Results:
- Both microperimetry and Octopus perimetry demonstrated similar structure-function relationships across overall and subnormal cpRNFL values.
- Regression analyses showed significant correlations for most sectors, though varying in strength.
- Specific R-squared values indicated moderate to strong correlations in certain sectors for both devices.
Conclusions:
- Microperimetry and Octopus perimetry exhibit comparable structure-function relationships in POAG.
- Fundus-tracking technology warrants further investigation in longitudinal glaucoma studies.
