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Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
What should we do about Coronary Calcification on Thoracic CT?
Oliver Llewellyn1, Michelle C Williams2
1Department of Radiology, Royal Infirmary of Edinburgh, United Kingdom of Great Britain and Northern Ireland.
Insights
Coronary artery calcification found on non-cardiac CT scans indicates higher cardiac risk. Reporting this incidental finding is recommended by guidelines and can prompt crucial cardiovascular risk assessments.
Area of Science:
- Radiology
- Cardiology
- Preventive Medicine
Background:
- Coronary artery calcification (CAC) is often incidentally detected on thoracic computed tomography (CT) scans ordered for non-cardiac reasons.
- On electrocardiogram-gated cardiac CT, CAC is a recognized indicator of coronary artery disease (CAD) and predicts future cardiac events.
Purpose of the Study:
- This review synthesizes current evidence and guidelines on reporting CAC identified in non-electrocardiogram-gated thoracic CT scans.
- To evaluate the clinical significance of incidental CAC findings in patients undergoing thoracic CT for non-cardiac indications.
Main Methods:
- Literature review of current evidence and guidelines.
- Analysis of the association between CAC on thoracic CT and cardiovascular outcomes.
- Comparison of CAC assessment on non-gated versus gated CT.
Main Results:
- CAC on routine thoracic CT is linked to increased risk of myocardial infarction and mortality.
- CAC can be reliably assessed on non-gated thoracic CT, comparable to gated CT.
- Guidelines advocate for reporting CAC found on thoracic CT, though radiologist consensus varies.
- Incidental CAC detection can identify individuals with previously unrecognized CAD, potentially leading to risk factor assessment and preventive treatment.
Conclusions:
- Reporting incidental CAC on thoracic CT is supported by guidelines and can facilitate early cardiovascular risk stratification.
- Future research should explore the impact of management changes based on thoracic CT-detected CAC and investigate automated CAC assessment using machine learning.
Purpose:
Coronary artery calcification is a frequent incidental finding on thoracic computed tomography (CT) performed for non-cardiac indications. On electrocardiogram-gated cardiac CT, it is an established marker of coronary artery disease and is associated with increased risk of subsequent cardiac events.
Materials And Methods:
This review discusses the current evidence and guidelines regarding the reporting of coronary artery calcification on non-electrocardiogram-gated thoracic CT performed for non-cardiac indications.
Results:
For patients undergoing routine thoracic CT, coronary artery calcification is associated with an increased risk of myocardial infarction and mortality. Coronary artery calcification can be accurately assessed on non-gated thoracic CT compared to gated CT. Guidelines support the reporting of coronary artery calcification on thoracic CT. However, radiologist opinions vary. The identification of coronary artery calcification on thoracic CT may identify patients with previously unknown coronary artery disease. For asymptomatic patients this may trigger an assessment of modifiable cardiovascular risk factors and guide the appropriate use of preventative medications.
Conclusion:
Future research will address whether changing management based on calcification on thoracic CT will improve outcomes and automated assessment of calcification using machine learning techniques.
Key Points:
· Coronary artery calcification is a frequent incidental finding on thoracic CT.. · The presence and severity of coronary artery calcification is associated with cardiac outcomes and mortality.. · Reporting coronary artery calcification on thoracic CT is supported by national and international guidelines..
Citation Format:
· Williams MC, Llewellyn O, . What Should We Do About Coronary Calcification on Thoracic CT?. Fortschr Röntgenstr 2022; 194: 833 - 840.
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