[Chinese multidisciplinary collaborative expert consensus for the diagnosis and treatment of Budd-Chiari syndrome

    Insights

    This consensus provides guidance for diagnosing and treating Budd-Chiari syndrome (B-CS), a hepatic vascular disease, in China. It addresses unique Chinese B-CS characteristics and promotes standardized, evidence-based clinical practice and research.

    Area of Science:

    • Hepatology
    • Vascular Medicine
    • Clinical Practice Guidelines

    Background:

    • Budd-Chiari syndrome (B-CS) is a complex hepatic vascular disease resulting from hepatic venous outflow obstruction.
    • Significant variations exist in the pathogenesis and treatment of B-CS between China and Western countries.
    • Unique epidemiological and clinical characteristics of B-CS in China necessitate tailored management strategies.

    Purpose of the Study:

    • To establish a multidisciplinary expert consensus for the diagnosis and treatment of Budd-Chiari syndrome in China.
    • To provide updated guidance reflecting the specific features of B-CS prevalent in the Chinese population.
    • To standardize and enhance the comprehensive management and research of B-CS within China.

    Main Methods:

    • A collaborative effort by domestic experts from the Professional Committee of Chinese Research Hospital Association.
    • Formulation of a consensus based on the current research status of B-CS in China.
    • Elaboration on epidemiology, pathogenesis, classification, clinical manifestations, diagnosis, and treatment.

    Main Results:

    • The consensus details the current understanding of B-CS epidemiology and pathogenesis in China.
    • It outlines standardized approaches for clinical classification, diagnosis, and treatment.
    • Identifies future research directions, emphasizing basic and high-level evidence clinical studies.

    Conclusions:

    • The 2021 version provides crucial guidance for clinicians managing B-CS in China.
    • It aims to standardize and improve the overall diagnosis and treatment of B-CS.
    • Encourages further basic and clinical research to advance the field in China.

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