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[Progress in diagnosis and treatment of gangrenous cholecystitis]

Z Li1, S Y Jia1, F Z Liu1

  • 1Department of General Surgery,Beijing Fengtai Hospital of Integrated Traditional and Western Medicine, Beijing 100072, China.

Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]
|March 10, 2022
PubMed

Insights

Gangrenous cholecystitis, a severe form of acute cholecystitis, progresses rapidly, leading to high mortality and frequent misdiagnosis. This review offers a comprehensive guide for clinicians on its pathogenesis, diagnosis, and treatment.

Area of Science:

  • Gastroenterology
  • Surgical Pathology

Background:

  • Gangrenous cholecystitis is a severe subtype of acute cholecystitis.
  • It is characterized by rapid disease progression, high mortality rates, and a propensity for misdiagnosis and missed diagnoses in clinical practice.
  • This critical condition has been notably overlooked in existing clinical guidelines.

Purpose of the Study:

  • To systematically review and consolidate information on gangrenous cholecystitis.
  • To provide clinicians with a clear and comprehensive diagnostic and therapeutic roadmap.
  • To address the gap in clinical guidelines regarding this serious condition.

Main Methods:

  • Systematic literature review.
  • Synthesis of information on pathogenesis.
  • Compilation of pathological manifestations, epidemiology, and clinical data.

Main Results:

  • Detailed summary of the pathogenesis and pathological findings.
  • Overview of epidemiological data.
  • Consolidated information on clinical presentation, diagnosis, and management strategies.

Conclusions:

  • Gangrenous cholecystitis requires urgent attention due to its severity and diagnostic challenges.
  • A comprehensive understanding of its multifaceted aspects is crucial for effective clinical management.
  • This review aims to equip clinicians with the necessary knowledge to improve patient outcomes.

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