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Postoperative Functional Analysis of Double Crush Versus Single Peripheral Nerve Decompression: A Retrospective Study
Conrad Stoy1,2, Pedro Beredjiklian2, Tyler Kreitz2
1Drexel University College of Medicine, Philadelphia, PA, USA.
Summary
Double crush syndrome patients with cervical spine and wrist decompression report worse outcomes than those with single-site decompression. Cervical radiculopathy significantly increases long-term disability post-surgery.
Area of Science:
- Neurosurgery
- Orthopedic Surgery
- Rehabilitation Medicine
Background:
- Double crush (DC) syndrome involves concurrent cervical radiculopathy and peripheral nerve compression.
- Patients with DC syndrome may experience increased nerve irritability and weakness postoperatively.
- Surgical decompression at both cervical spine and wrist may lead to inferior patient-reported outcomes compared to single-site decompression.
Purpose of the Study:
- To compare patient-reported outcomes following combined cervical and wrist decompression versus single-site decompression.
- To evaluate the impact of double crush syndrome on postoperative functional disability and pain.
Main Methods:
- Retrospective analysis of 477 patients undergoing anterior cervical decompression and fusion (ACDF), carpal tunnel release (CTR), or both (DC) within 5 years.
- Postoperative outcomes assessed using Disabilities of the Arm, Shoulder, and Hand (QuickDASH), Neck Disability Index, and visual analog scale (VAS) scores.
- Outcomes collected at an average of 2 years postoperatively.
Main Results:
- Higher QuickDASH scores in the DC group compared to the CTR group (36 vs 22, P < .0002).
- ACDF group showed significantly higher postoperative disability than the DC group (50 vs 36, P < .017).
- CTR group reported greater arm pain intensity than the DC group (5.7 vs 3.6, P < .01).
Conclusions:
- Combined ACDF and CTR result in greater postoperative disability than CTR alone.
- Cervical radiculopathy appears to contribute significantly to long-term postoperative disability.
- Higher postoperative arm pain in the CTR-alone group suggests potential undiagnosed cervical radiculopathy.

