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Updated: Sep 30, 2025
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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
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Staphylococcus aureus infections after elective pediatric surgeries
Iona M Munjal1, Jill Dreyfus2, Holly Yu1
1Pfizer, Pearl River, New York.
Infection Control and Hospital Epidemiology
|March 11, 2022
Summary
Pediatric patients undergoing elective surgery face a risk of Staphylococcus aureus infections, especially younger children. Continued infection prevention and surveillance are crucial post-surgery.
Area of Science:
- Infectious Disease Epidemiology
- Pediatric Surgery Outcomes
- Healthcare-Associated Infections
Background:
- Postoperative infections pose a significant risk in pediatric surgery.
- Staphylococcus aureus is a common pathogen causing healthcare-associated infections.
Purpose of the Study:
- To determine the 180-day cumulative incidence of Staphylococcus aureus infections following elective pediatric surgeries.
- To analyze infection rates based on patient age and surgical setting (inpatient vs. outpatient).
Main Methods:
- Retrospective cohort study using the Premier Healthcare database (PHD).
- Included pediatric patients (<18 years) undergoing elective surgeries between 2010 and 2015.
- Defined Staphylococcus aureus infections (bloodstream, surgical site, other) using microbiology and diagnosis codes.
Main Results:
- Overall 180-day incidence of Staphylococcus aureus infections was 1.79% for inpatient and 0.36% for outpatient surgeries.
- Younger children (<2 years) had higher infection rates in both settings.
- Methicillin-resistant Staphylococcus aureus (MRSA) incidence was significantly higher after inpatient surgeries.
Conclusions:
- Postoperative Staphylococcus aureus infections represent a considerable burden in pediatric patients, particularly in younger children.
- Findings highlight the need for enhanced infection prevention strategies and extended surveillance.
- Age and surgical setting are critical factors influencing infection risk.
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