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Cancer risk estimation using American College of Radiology Thyroid Imaging Reporting and Data System for
Matthew V Dickey1, Anne Nguyen1, Sam M Wiseman1
1Department of Surgery, St. Paul's Hospital & University of British Columbia, C303-1081 Burrard Street Vancouver, BC, V6Z 1Y6, Vancouver, British Columbia, Canada.
Background:
We sought to determine if using the ACR TI-RADS ultrasound score combined with the Bethesda diagnosis can help augment thyroid cancer risk estimation.
Methods:
TI-RADS scores and Bethesda diagnoses were collected for patients treated in our center who had undergone thyroidectomy. Data from 186 patients with both TI-RADS scores and Bethesda diagnosis, and Bethesda diagnosis alone, were analyzed by multivariable regression analysis and observed for whether the pathology was benign or malignant.
Results:
The regression analysis model showed that as the TI-RADS score increases, the odds of malignancy increases as well. The predictive value of the odds of malignancy in a thyroid nodule using both Bethesda diagnosis and TI-RADS score together was more powerful than the odds given using the Bethesda diagnosis alone.
Conclusions:
Our model shows that the ACR TI-RADS score may assist with preoperative decision-making for patients with cytologically indeterminate thyroid nodules when combined with Bethesda diagnosis.
