Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Dobutamine in vascular surgery].

R Muchada, B Lavandier, S Estanove

    Cahiers D'Anesthesiologie
    |May 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Correction of a Complex Foot Deformity With V and Y Osteotomy and Ilizarov Method.

    The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons·2022
    Same author

    [Contribution of low-intensity pulsed ultrasounds to bone regeneration].

    Revue de stomatologie et de chirurgie maxillo-faciale·2011
    Same author

    [The impact of low intensity pulsed ultrasound on mouse skull bone osteoblast cultures].

    Revue de stomatologie et de chirurgie maxillo-faciale·2010
    Same author

    Morphological analysis of the interstitial ultrasonic ablation in porcine liver in vivo.

    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes·2008
    Same author

    [Craniofacial approach for orbital tumors and ultrasonic bone cutting].

    Journal francais d'ophtalmologie·2007
    Same author

    Ultrasonic osteotomy as a new technique in craniomaxillofacial surgery.

    International journal of oral and maxillofacial surgery·2007
    Same journal

    [The Ombredanne equipment].

    Cahiers d'anesthesiologie·1996
    Same journal

    [Comparison of the efficacy of 2 antiseptic solutions in the prevention of infection from peridural catheters].

    Cahiers d'anesthesiologie·1996
    Same journal

    [Caudal and spinal anesthesia in sub-umbilical surgery in children. Apropos of 1875 cases].

    Cahiers d'anesthesiologie·1996
    Same journal

    [Evaluation of the cost of autologous erythrocyte concentrates in a hospital].

    Cahiers d'anesthesiologie·1996
    Same journal

    [Combination of propofol-ketamine-vecuronium for total intravenous anesthesia under hazardous conditions].

    Cahiers d'anesthesiologie·1996
    Same journal

    [Venous surgery of the lower limb: value of nerve blocks].

    Cahiers d'anesthesiologie·1996
    See all related articles

    Dobutamine infusion during surgery improved hemodynamic parameters, maintaining aortic output and systolic volume while increasing heart rate. This contrasts with placebo, which significantly raised vascular resistance and H+ concentration.

    Area of Science:

    • Cardiology
    • Anesthesiology
    • Critical Care Medicine

    Background:

    • Non-invasive monitoring of hemodynamic parameters is crucial during surgery.
    • Maintaining adequate cardiac output and managing vascular resistance are key challenges in surgical patients.

    Purpose of the Study:

    • To evaluate the effect of dobutamine on hemodynamic parameters in patients undergoing non-coronary vascular surgery.
    • To compare dobutamine's effects against a placebo in a double-blind study.

    Main Methods:

    • 12 patients were divided into two groups: dobutamine infusion (Group 1) and placebo (Group 2).
    • Hemodynamic parameters, including aortic output and systolic volume, were measured non-invasively using an esophageal probe with echocardiography and Doppler.
    • Cardiac frequency, total systemic vascular resistance, diuresis, and H+ concentration were monitored.

    Related Experiment Videos

    Main Results:

    • Group 1 (dobutamine) maintained similar aortic output and systolic volume compared to pre-anesthesia levels, while Group 2 (placebo) showed significantly lower values.
    • Cardiac frequency increased in Group 1, whereas Group 2 experienced a 207% rise in vascular resistance and increased H+ concentration.
    • Mean diuresis was significantly higher in Group 1 (144 ml/h) compared to Group 2 (43.6 ml/h).

    Conclusions:

    • Dobutamine infusion effectively supports hemodynamic stability during non-coronary vascular surgery.
    • Dobutamine helps maintain adequate cardiac output and improves diuresis without significantly altering vascular resistance.
    • Placebo administration leads to detrimental hemodynamic changes, including increased vascular resistance and acidosis.