Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

5.3K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
5.3K
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

251
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
251
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

180
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
180

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Understanding Patient Perspectives on Radiation Tattoos.

Advances in radiation oncology·2026
Same author

Post-thyrotoxicosis weight gain: time to stratify and treat?

Nature reviews. Endocrinology·2026
Same author

An Exploratory Study of Heat Shock Protein Changes in Women with Unexplained Infertility.

International journal of molecular sciences·2026
Same author

Postoperative Dysphagia After Aortic Surgery and Performance of Bedside Swallow Screening: A Retrospective Cohort Study.

Journal of cardiothoracic and vascular anesthesia·2026
Same author

Fenofibrate and progression of retinopathy in adults with diabetes: the randomised placebo-controlled LENS trial.

Health technology assessment (Winchester, England)·2026
Same author

An Exploratory Study of Matrix Metalloproteinase Protein Changes in Unexplained Infertility.

Life (Basel, Switzerland)·2026
Same journal

Supraphysiological Glucocorticoid Doses and Pitfalls of Annual Biomarker Monitoring in Adults With CAH.

Clinical endocrinology·2026
Same journal

Subacute Thyroiditis in Denmark: A Nationwide Study of 1763 Cases.

Clinical endocrinology·2026
Same journal

Pubertal Dynamics of Sertoli and Leydig Cell Dysfunction in Klinefelter Syndrome.

Clinical endocrinology·2026
Same journal

Regarding Non-Classical Presentations of Rare Hereditary Hypoparathyroidism: A Case Series of CASR, GNA11, and GATA3 Mutations in Parathyroidology.

Clinical endocrinology·2026
Same journal

Dual Metabolic Burden of Polyendocrine Metabolic Ovarian Syndrome (PMOS) and Gestational Diabetes in Pregnancy: Impact on Neonatal Anthropometry: Insights From the Born in Bradford Cohort.

Clinical endocrinology·2026
Same journal

Preoperative CALLY Index for Identifying Atypical Parathyroid Tumors.

Clinical endocrinology·2026
See all related articles

Related Experiment Video

Updated: Sep 30, 2025

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
09:49

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

Published on: April 24, 2020

10.1K

Postradioiodine Graves' management: The PRAGMA study.

Petros Perros1, Ansu Basu2, Kristien Boelaert3

  • 1Department of Endocrinology, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

Clinical Endocrinology
|March 11, 2022
PubMed
Summary
This summary is machine-generated.

Thyroid function instability is common after radioiodine treatment for Graves' disease, with high rates of hypothyroidism and hyperthyroidism. Current management strategies show minimal differences in effectiveness for addressing this dysthyroidism.

Keywords:
Graves' diseasehyperthyroidismhypothyroidismradioiodinethyroid

More Related Videos

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

3.8K
Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
04:09

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Published on: September 20, 2024

442

Related Experiment Videos

Last Updated: Sep 30, 2025

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
09:49

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods

Published on: April 24, 2020

10.1K
Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

3.8K
Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
04:09

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter

Published on: September 20, 2024

442

Area of Science:

  • Endocrinology
  • Nuclear Medicine
  • Thyroidology

Background:

  • Radioiodine (RI) treatment for Graves' disease can lead to unstable thyroid function post-treatment.
  • Monitoring and managing thyroid status after RI is crucial for patient outcomes.

Purpose of the Study:

  • To quantify the frequency of abnormal thyroid function following RI treatment for Graves' disease.
  • To compare the effectiveness of common post-RI management strategies.

Main Methods:

  • Retrospective, multicentre observational study of adult patients with Graves' disease treated with RI.
  • 12-month follow-up assessing thyroid function (TSH, FT4) and management strategies (antithyroid drugs, levothyroxine, or combination).

Main Results:

  • Hypothyroidism occurred in 80.7% and hyperthyroidism in 48.6% of 812 patients post-RI.
  • Management strategies (antithyroid drugs, levothyroxine, combination) showed small differences in effectiveness.
  • Low adherence to national guidelines for thyroid function monitoring (21.4%-28.7%) in the first 6 months.

Conclusions:

  • Dysthyroidism is common in the 12 months following RI treatment for Graves' disease.
  • Current management strategies alone are unlikely to resolve the high frequency of dysthyroidism.
  • Significant variations in practice and outcomes exist between treatment centers.