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Dermoscopic features of nevoid melanoma: a retrospective study
Francesco Bellinato1, Paolo Rosina2, Marco Zarattini2
1Section of Dermatology and Venereology, Department of Medicine, University of Verona, Verona, Italy - francesco.bellinato@univr.it.
Italian Journal of Dermatology and Venereology
|March 11, 2022
Summary
Nevoid melanoma (NeM) often mimics benign nevi, making diagnosis difficult. Dermoscopic clues like enlargement and irregular pigmentation can aid in identifying NeM, even when it appears nevus-like.
Area of Science:
- Dermatology
- Oncology
- Dermoscopy
Background:
- Nevoid melanoma (NeM) is a rare melanoma variant that clinically resembles melanocytic nevi.
- Accurate diagnosis is crucial due to potential for malignancy.
Purpose of the Study:
- To systematically review and characterize the dermoscopic features of nevoid melanoma (NeM).
- To identify diagnostic clues that differentiate NeM from benign nevi and other melanomas.
Main Methods:
- Retrospective analysis of dermoscopic features in 20 NeM cases compared to 40 superficial spreading melanomas (SSMs).
- Literature search of PubMed/Medline for studies reporting dermoscopic features of histopathologically confirmed NeM.
Main Results:
- NeM frequently presented with nevus-like patterns (60% in study, 53% in literature).
- Dermoscopic changes in NeM included enlargement, irregular dots/globules, irregular pigmentation, and atypical vascular patterns.
- Multicomponent and amelanotic patterns were less common but showed distinct features like blue-white veil and milia-like cysts.
Conclusions:
- Dermoscopy of NeM is challenging due to its frequent nevus-like appearance.
- Recognizing specific dermoscopic changes and alterations is key for accurate NeM identification.
