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[Craniorachischisis: a case report].

Christian Emmanuel Rodríguez-Partida¹, Iván André Guzmán-Amador¹, Félix José Molina-Aguiar¹

¹Instituto Mexicano del Seguro Social, Hospital General Regional No. 1, Departamento de Ginecología y Obstetricia. Mérida, Yucatán, México.

Revista Medica Del Instituto Mexicano Del Seguro Social

|March 11, 2022

Summary

Craniorachischisis, a severe neural tube defect, is a rare and fatal condition. Early diagnosis is crucial for managing pregnancies involving this severe congenital anomaly.

Keywords:

Anencephaly Folic Acid Neural Tube Defects Spinal Dysraphism

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Area of Science:

Obstetrics and Gynecology
Developmental Biology
Medical Imaging

Background:

Neural tube defects (NTDs) are complex congenital anomalies with multifactorial origins.
NTDs arise from failed closure of the neural tube, affecting the central nervous system and surrounding structures.
These defects encompass a wide spectrum of severity and involve various tissues including skin, bone, and spinal cord.

Observation:

A case report details a 36-year-old woman at 25.3 weeks gestation with a history of anencephaly in a prior pregnancy.
The current pregnancy was characterized by suboptimal prenatal care.
Obstetric ultrasound confirmed a diagnosis of craniorachischisis.

Findings:

Craniorachischisis represents an extremely rare and severe form of neural tube defect.
The condition is characterized by a failure of neural tube closure, resulting in exposed neural tissue.
Diagnosis via second-trimester ultrasound is critical for understanding the prognosis.

Implications:

Craniorachischisis is universally considered incompatible with life, necessitating early diagnosis and management planning.
This case underscores the importance of advanced prenatal imaging in identifying severe congenital anomalies.
Understanding the presentation and prognosis of craniorachischisis is vital for genetic counseling and obstetric decision-making.