[Progressive myositis ossificans: Case report]

Area of Science:

• Connective tissue disorders
• Oncology
• Radiology

Background:

• Myositis ossificans progressiva (MOP) is a rare hereditary connective tissue disease characterized by heterotopic ossification.
• MOP has an uncertain behavior and has been exceptionally linked to neoplasms.
• This study aimed to investigate the coexistence of MOP with mesodermal neoplasms.

Observation:

• A 27-year-old female presented with gluteal and ischitibial muscle pain, leading to limited mobility.
• Imaging revealed heterogeneous radiolucency in the thighs and pelvis, consistent with myositis ossificans of the hip.
• The patient also presented with gastric symptoms, diagnosed as diffuse gastric carcinoma, and an ovarian tumor.

Findings:

• The case highlights a rare association between Myositis Ossificans Progressiva, gastric carcinoma, and an ovarian tumor.
• Limited literature exists on the co-occurrence of these three conditions, indicating a need for further research.

Implications:

• Increased awareness of MOP's potential association with neoplasms is vital for comprehensive patient diagnosis.
• While no cure for MOP exists, timely diagnosis facilitates rehabilitation and improves quality of life.
• Further research into the pathophysiology of MOP and its association with mesodermal neoplasms is warranted.