Related Experiment Video
Updated: Sep 7, 2026

Detection of Toxin Translocation into the Host Cytosol by Surface Plasmon Resonance
Published on: January 3, 2012
Abstract:
Bacteria and their toxins are responsible for an enormous burden of diarrhoeal disease. Knowledge about the toxins and their mechanisms of action is limited. Thus, although considerable information is available about the mechanism of action of cholera toxin and a small number of heat-stable enterotoxins, information on the role and action of many others is incomplete. The demonstration of a toxic effect in a test system does not necessarily imply that that activity is relevant to the pathogenesis of the diarrhoea. On the other hand, the absence of a toxic effect in experimental systems does not eliminate the possibility that a toxin is responsible for a particular organism's clinical effects. This is a field of active research and much more work is clearly required.
More Related Videos
09:39Determination of Tolerable Fatty Acids and Cholera Toxin Concentrations Using Human Intestinal Epithelial Cells and BALB/c Mouse Macrophages
Published on: May 30, 2013
09:12A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection
Published on: June 15, 2018
Related Concept Videos
Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents
Adsorbents...
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents
Bacterial Toxins
Determinants of Bacterial Pathogenicity and Virulence
Bacterial Gastroenteritis
Cholera