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Published on: June 12, 2021
The landscape of cardiogenic shock: epidemiology and current definitions
Cesar Palacios Ordonez1, Arthur Reshad Garan
1Division of Cardiology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Insights
Cardiogenic shock mortality remains high, especially for non-acute myocardial infarction causes. Novel classification systems are needed to improve research and treatment for this critical condition.
Area of Science:
- Cardiology
- Critical Care Medicine
Background:
- Cardiogenic shock (CS) continues to have high mortality despite advancements in treatment.
- While acute myocardial infarction (AMI) is a common cause, CS from other etiologies is increasingly recognized.
Purpose of the Study:
- To review the evolving epidemiology of cardiogenic shock.
- To discuss novel classification schemas for cardiogenic shock.
- To explore future perspectives in cardiogenic shock research and treatment.
Main Methods:
- Literature review of cardiogenic shock.
- Analysis of epidemiological trends.
- Discussion of emerging classification systems.
Main Results:
- Non-AMI causes of cardiogenic shock, such as acute on chronic heart failure and noncoronary structural heart disease, are becoming more prevalent.
- Mortality rates for cardiogenic shock remain unacceptably high.
- Existing classification systems may not adequately capture the diverse etiologies of CS.
Conclusions:
- There is a critical need for effective treatments for cardiogenic shock, particularly for non-AMI related cases.
- Novel classification systems are essential to advance research and improve patient outcomes in cardiogenic shock.
- Further research into the epidemiology and treatment of diverse cardiogenic shock etiologies is warranted.
Purpose Of Review:
Despite novel technologies for treating shock patients, cardiogenic shock mortality remains high. Trends of cardiogenic shock associated with acute myocardial infarction (AMI) have previously been described, though little is known about cardiogenic shock resulting from other causes, which has progressively been documented as a distinct entity from AMI-cardiogenic shock. Herein, we review the evolving epidemiology, novel classification schema, and future perspectives of cardiogenic shock.
Recent Findings:
While AMI or mechanical complications of AMI are the most common causes, the incidence of etiologies of cardiogenic shock not related to AMI, particularly acute on chronic heart failure, may be increasing, with a growing burden of noncoronary structural heart disease.
Summary:
Mortality in cardiogenic shock remains high. Overall, these findings highlight the need to address the lack of effective treatments in this field, particularly for cardiogenic shock caused by diseases other than AMI. Novel classification systems may facilitate cardiogenic shock research.
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