Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Storage01:23

Storage

144
A schema is a mental framework that helps individuals organize and interpret information. Schemata, formed from previous experiences, influence how we process new information: how we encode it, the inferences we make, and how we retrieve it. For instance, a schema for what a typical classroom looks like might include desks, a teacher's desk, a whiteboard, and students in such an environment. This expectation helps us quickly understand and navigate new classrooms without needing to analyze...
144
Implicit Memories01:24

Implicit Memories

209
Implicit memories, also known as non-declarative memories, are long-term memories that function outside of conscious awareness. These memories influence behavior and skills without explicit knowledge. This type of memory is evident in tasks like playing tennis, snowboarding, and texting. Implicit memory has three subsystems: procedural memory, conditioning, and priming. This type of memory is essential in various activities, from everyday tasks to specialized skills.
One key aspect of implicit...
209

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Differential Effects of Hippocampal Astrocytic Glutamate Uptake Modulation on Aversive Memory Formation and Expression.

Journal of neurochemistry·2025
Same author

The PERCIVAL detector: first user experiments.

Journal of synchrotron radiation·2023
Same author

Housing and accessibility after the COVID-19 pandemic: Rebuilding for resilience, equity and sustainable mobility.

Transport policy·2022
Same author

Pulse Energy and Pulse Duration Effects in the Ionization and Fragmentation of Iodomethane by Ultraintense Hard X Rays.

Physical review letters·2021
Same author

Tissue-Sparing Outcome of Mohs Micrographic Surgery in Squamous Cell Carcinomas.

Actas dermo-sifiliograficas·2020
Same author

Novelty Improves the Formation and Persistence of Memory in a Naturalistic School Scenario.

Frontiers in psychology·2020
Same journal

Contribution of muscarinic acetylcholine receptors to bottom-up amplification of frontal and parietal cortical responses to rare deviant tones in rats.

Neuroscience·2026
Same journal

Developmental switch of GABAergic signaling in starburst amacrine cells driven by chloride transporter dynamics.

Neuroscience·2026
Same journal

Epileptiform discharges are associated with increased theta activity over time in patients with Lewy body dementia.

Neuroscience·2026
Same journal

Response times from gap detection threshold testing relate to cognitive processing speed in young adults.

Neuroscience·2026
Same journal

The timing of visual selective attention in fronto-parietal network: TMS behavioral and brain structural evidence.

Neuroscience·2026
Same journal

Effects of silencing tuberomammillary nucleus histidine decarboxylase-lineage neurons on behavioral responses in a mouse model of motion sickness.

Neuroscience·2026
See all related articles

Related Experiment Video

Updated: Sep 30, 2025

The Double-H Maze: A Robust Behavioral Test for Learning and Memory in Rodents
09:01

The Double-H Maze: A Robust Behavioral Test for Learning and Memory in Rodents

Published on: July 8, 2015

12.7K

Persistence of Spatial Memory Induced by Spaced Training Involves a Behavioral-Tagging Process.

J Correa1, R Tintorelli1, P Budriesi1

  • 1Facultad de Medicina. Universidad de Buenos Aires. Buenos Aires, Argentina; Laboratorio de Memoria, Instituto de Biología Celular y Neurociencias "Prof. E. De Robertis" (IBCN), Facultad de Medicina, UBA-CONICET, Buenos Aires, Argentina.

Neuroscience
|March 11, 2022
PubMed
Summary
This summary is machine-generated.

Spaced training enhances long-term memory (LTM) persistence. Retraining activates specific brain pathways, utilizing plasticity-related proteins and learning tags to maintain memories, suggesting memory expression is key for LTM persistence.

Keywords:
hippocampuslearning taglong-term memory persistencememory retrievalspaced learningspatial object recognition

More Related Videos

A Behavioral Assay for Investigating the Role of Spatial Memory During Instinctive Defense in Mice
05:49

A Behavioral Assay for Investigating the Role of Spatial Memory During Instinctive Defense in Mice

Published on: July 21, 2018

9.7K
Investigation of Synaptic Tagging/Capture and Cross-capture using Acute Hippocampal Slices from Rodents
11:29

Investigation of Synaptic Tagging/Capture and Cross-capture using Acute Hippocampal Slices from Rodents

Published on: September 4, 2015

14.2K

Related Experiment Videos

Last Updated: Sep 30, 2025

The Double-H Maze: A Robust Behavioral Test for Learning and Memory in Rodents
09:01

The Double-H Maze: A Robust Behavioral Test for Learning and Memory in Rodents

Published on: July 8, 2015

12.7K
A Behavioral Assay for Investigating the Role of Spatial Memory During Instinctive Defense in Mice
05:49

A Behavioral Assay for Investigating the Role of Spatial Memory During Instinctive Defense in Mice

Published on: July 21, 2018

9.7K
Investigation of Synaptic Tagging/Capture and Cross-capture using Acute Hippocampal Slices from Rodents
11:29

Investigation of Synaptic Tagging/Capture and Cross-capture using Acute Hippocampal Slices from Rodents

Published on: September 4, 2015

14.2K

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Molecular Biology

Background:

  • Spaced training improves memory formation and persistence.
  • Long-term memory (LTM) is characterized by its persistence over time.
  • Understanding the mechanisms behind LTM persistence is crucial for cognitive research.

Purpose of the Study:

  • To investigate the process promoting LTM persistence through spaced learning.
  • To identify the neural and molecular mechanisms underlying memory persistence.
  • To explore the role of the Behavioral Tagging (BT) mechanism in LTM persistence.

Main Methods:

  • Utilized the spatial object recognition (SOR) task in rats.
  • Implemented a two-session training protocol with varying inter-trial intervals.
  • Analyzed molecular mechanisms including ERKs1/2 activity and AMPA receptor availability.

Main Results:

  • A first training session induced LTM formation but not persistence.
  • A second training session, applied 1 day after the first, promoted memory persistence.
  • Memory expression, not reinforcement or reconsolidation, was necessary for persistence after retraining.
  • ERKs1/2 activity and GluA2-containing AMPA receptors were implicated in the molecular mechanisms.

Conclusions:

  • The Behavioral Tagging (BT) mechanism, involving learning tags and plasticity-related proteins (PRPs), is proposed to underlie memory persistence.
  • Retraining triggers the synthesis of PRPs and the setting of learning tags, crucial for maintaining SOR memory persistence.
  • Memory expression mechanisms are vital for promoting LTM persistence following spaced retraining.