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Updated: Aug 10, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Postpartum Group A strep sepsis after third trimester uterine prolapse: case report and literature review
Simone Reaves1, Vaishali Mehta2, Jason K Baxter3
1Department of Obstetrics and Gynecology, Thomas Jefferson University Hospital, Philadelphia, PA, USA. simone.reaves@jefferson.edu.
Introduction:
Uterine prolapse in pregnancy is an uncommon occurrence that can lead to a wide spectrum of complications. Postpartum Group A Streptococcus (GAS) endometritis is a rare but life-threatening condition. Our aim was to review the literature regarding management of prolapse in pregnancy and maternal infection as a rare complication.
Methods And Results:
We present a case of uterine prolapse with cervical elongation presenting in the third trimester. The patient's prolapse was refractory to pessary management. She was induced at 36 weeks due to an abnormal fetal heart tracing and had an uncomplicated vaginal delivery. Her postpartum course was complicated by GAS endometritis and septic shock. She recovered after antibiotic therapy and her prolapse did not recur postpartum.
Conclusion:
Prolapse during pregnancy carries a risk of several complications but does not preclude a vaginal delivery. Management must be patient-centered and individualized. GAS sepsis is a potential, rare, and life-threatening postpartum complication requiring swift identification and treatment.
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