Related Experiment Video
Updated: Aug 4, 2026
05:52
Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
15.0K
Psychosis After Infection With SARS-CoV-2 in an Adolescent: A Case Report
Reena Thomas1, Michael J Hernandez2, Roy Thomas3
1Johns Hopkins All Children's Hospital, St. Petersburg, Florida.
Summary
A third of COVID-19 patients experience long-term neuropsychiatric issues, including psychosis. These symptoms, often presenting acutely with hallucinations, may indicate a reversible medical cause.
Area of Science:
- Neurology
- Psychiatry
- Infectious Diseases
Background:
- Coronavirus disease 2019 (COVID-19) can lead to persistent neuropsychiatric complications in a significant portion of patients.
- Neuropsychiatric symptoms following COVID-19 infection are increasingly recognized, with case reports highlighting associations with psychosis in adults.
Observation:
- A notable percentage of individuals recovering from COVID-19 report enduring symptoms affecting cognitive and emotional functions.
- Psychotic symptoms, such as hallucinations and altered perceptions, have been observed in the context of COVID-19 infection.
Findings:
- Up to one-third of patients with COVID-19 may develop long-term neuropsychiatric conditions, including anxiety, depression, brain fog, psychosis, seizures, and suicidal ideation.
- First-episode psychosis following COVID-19 can present with acute onset, visual or tactile hallucinations, and other neurological signs, suggesting a potential medical etiology.
Implications:
- Recognizing these neuropsychiatric sequelae is crucial for timely diagnosis and management of post-COVID-19 neurological and psychiatric disorders.
- The potential reversibility of psychosis linked to medical illness in the context of COVID-19 underscores the need for comprehensive patient evaluation.
- Further research is warranted to elucidate the mechanisms underlying COVID-19-associated neuropsychiatric symptoms and to develop targeted therapeutic strategies.
More Related Videos
07:31Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
Published on: May 15, 2020
7.2K
08:41Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
2.9K
Related Concept Videos
01:27Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
01:17Schizophrenia
Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.
01:29Psychological and Sociocultural Causes of Schizophrenia
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
01:28Rabies
Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
01:29Coronavirus
Coronaviruses, including the severe acute respiratory syndrome coronavirus (SARS-CoV), are enveloped viruses characterized by their single-stranded, positive-sense RNA genome and helical nucleocapsid structure. The hallmark of these viruses is their club-shaped spike (S) glycoproteins that protrude from the viral envelope, facilitating attachment to host cells. Typically, coronaviruses infect the upper respiratory tract, often causing mild or asymptomatic disease. However, certain strains like...
01:19Encephalitis l: Introduction
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...