Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

68
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
68
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

82
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
82
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

90
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
90
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

62
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
62
Kidney Structure01:45

Kidney Structure

70.9K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
70.9K
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

116
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
116

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Harnessing HLA Divergence for Improved Donor Selection in Haploidentical Haematopoietic Stem Cell Transplantation.

HLA·2025
Same author

Insights into the localized corrosion initiation mechanisms of alloy 718.

Heliyon·2025
Same author

Diagnostic Test Accuracy of Urinary DNA Methylation-based Biomarkers for the Detection of Primary and Recurrent Bladder Cancer: A Systematic Review and Meta-analysis.

European urology focus·2024
Same author

Appropriateness of prescribing profiles and intake adherence to non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: analysis of a retrospective longitudinal study using real-world data from Northern Portugal (AF-React Study).

BMJ open·2024
Same author

AF-React study: Prevalence of thrombotic events in patients with atrial fibrillation receiving NOACs - real-world data analysis from northern Portugal primary healthcare.

Frontiers in medicine·2024
Same author

Exploring the electrical robustness of conductive textile fasteners for wearable devices in different human motion conditions.

Scientific reports·2024

Related Experiment Video

Updated: Sep 30, 2025

Mouse Kidney Transplantation: Models of Allograft Rejection
16:15

Mouse Kidney Transplantation: Models of Allograft Rejection

Published on: October 11, 2014

21.0K

Kidney allocation rules simulator.

Bruno A Lima1, Teresa S Henriques2, Helena Alves3

  • 1Oficina de Bioestatistica, Transplant Open Registry, Ermesinde, Portugal.

Transplant Immunology
|March 12, 2022
PubMed
Summary
This summary is machine-generated.

Developing fair kidney allocation rules requires predictive simulations. The Kidney Allocation Rules Simulator (KARS) application helps test different systems to optimize deceased donor kidney distribution and reduce waitlist returns.

Keywords:
Allocation systemClinical decision-makingKidney transplantation

More Related Videos

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach
09:15

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach

Published on: May 7, 2019

16.1K
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

4.6K

Related Experiment Videos

Last Updated: Sep 30, 2025

Mouse Kidney Transplantation: Models of Allograft Rejection
16:15

Mouse Kidney Transplantation: Models of Allograft Rejection

Published on: October 11, 2014

21.0K
Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach
09:15

Orthotopic Rat Kidney Transplantation: A Novel and Simplified Surgical Approach

Published on: May 7, 2019

16.1K
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

4.6K

Area of Science:

  • Nephrology
  • Transplantation Immunology
  • Health Informatics

Background:

  • Kidney transplantation faces a critical shortage of deceased donor organs, impacting waitlisted candidates.
  • Predicting transplant success is crucial for efficient organ allocation and minimizing patient returns to the waitlist.

Purpose of the Study:

  • To introduce the Kidney Allocation Rules Simulator (KARS) application for testing various kidney allocation systems.
  • To support the evidence-based definition of deceased donor kidney allocation rules through simulation.

Main Methods:

  • KARS simulates different kidney allocation systems using donor and recipient data, including anti-HLA antibody information.
  • The application allows for the testing of allocation rules from Portugal, the UK, Eurotransplant, and a color priority system.

Main Results:

  • The simulator outputs potential donor-recipient pairs based on simulated allocation rules.
  • It facilitates the evaluation of different allocation strategies to improve organ utilization.

Conclusions:

  • Data-driven simulations are essential for defining effective kidney allocation rules.
  • KARS provides a valuable tool for optimizing the distribution of scarce deceased donor kidneys and improving transplant outcomes.