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Red blood cell distribution width in elderly populations and its implications for clinical studies

John L Frater1, M Yadira Hurley2

  • 1Department of Pathology and Immunology, Washington University, St Louis, MO, United States of America.

Archives of Gerontology and Geriatrics
|March 12, 2022
PubMed
Abstract

No abstract available in PubMed .

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Volume of Distribution01:20

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The apparent volume of distribution (Vd) is a crucial pharmacokinetic parameter representing the hypothetical body fluid volume into which a drug disperses. It is calculated based on the total amount of drug in the body (estimated from the administered dose and bioavailability) divided by the plasma drug concentration. The total amount of drug in the body does not directly refer to the dose given but is derived by accounting for absorption, distribution, metabolism, and excretion processes.
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