Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lectin binding to normal human endometrium.

V Bychkov, P D Toto

    Gynecologic and Obstetric Investigation
    |January 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Lectins like peanut agglutinin (PNA) and Ulex europaeus (UEA-I) show changes in endometrial binding during the menstrual cycle and pregnancy. Wheat germ agglutinin (WGA) and Ricinus communis (RCA-I) also alter binding, while Concanavalin A (Con A) binds decidual cells.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    HPV status and its genomic integration affect survival of patients with cervical cancer.

    Neoplasma·2018
    Same author

    Constraints on Oscillation Parameters from ν_{e} Appearance and ν_{μ} Disappearance in NOvA.

    Physical review letters·2017
    Same author

    Measurement of the Neutrino Mixing Angle θ_{23} in NOvA.

    Physical review letters·2017
    Same author

    Multidimensional instability and dynamics of spin avalanches in crystals of nanomagnets.

    Physical review letters·2014
    Same author

    Ultrafast spin avalanches in crystals of nanomagnets in terms of magnetic detonation.

    Physical review letters·2011
    Same author

    Speedup of doping fronts in organic semiconductors through plasma instability.

    Physical review letters·2011
    Same journal

    Vaginal Estrogen for Urinary Tract Infection Prevention: A Narrative Review of Evidence, Guidelines, and Regulatory Gaps.

    Gynecologic and obstetric investigation·2026
    Same journal

    Auxiliary data as surrogates for SCORE2 risk calculator inputs - design and methodology of the Frauenherzen study in apparently healthy women aged 40-69 years.

    Gynecologic and obstetric investigation·2026
    Same journal

    Comparison of colpocleisis and long-term pessary therapy in the management of severe pelvic organ prolapse - A retrospective observational study.

    Gynecologic and obstetric investigation·2026
    Same journal

    Société Suisse de Gynécologie et d'Obstétrique (SGGG) Congress Congrès annuel de Gynécologie Suisse.

    Gynecologic and obstetric investigation·2026
    Same journal

    Comparative Study of DHEA vs. Femarelle® on Menopausal Systemic and Genitourinary Syndrome.

    Gynecologic and obstetric investigation·2026
    Same journal

    The Role Of Dietary Supplements in The Management Of Endometriosis-Related Symptoms: Current Evidence Based on A Systematic Review Of Randomized Controlled Trials.

    Gynecologic and obstetric investigation·2026
    See all related articles

    Area of Science:

    • Reproductive biology
    • Histology
    • Biochemistry

    Background:

    • Endometrial receptivity is crucial for successful implantation.
    • Changes in endometrial glycoproteins are associated with the menstrual cycle and pregnancy.
    • Lectins are proteins that bind specific carbohydrate structures, offering insights into cellular composition.

    Purpose of the Study:

    • To map the binding sites of specific lectins in the human endometrium.
    • To investigate lectin binding patterns across the menstrual cycle and early pregnancy.
    • To correlate lectin expression with endometrial changes.

    Main Methods:

    • Avidin-biotin-peroxidase labeling technique was employed.
    • Localization of binding sites for peanut agglutinin (PNA), Ulex europaeus (UEA-I), wheat germ agglutinin (WGA), concanavalin A (Con A), and Ricinus communis (RCA-I) was performed.

    Related Experiment Videos

  • Thirty endometrial samples from different menstrual cycle stages and early pregnancy were analyzed.

    • Main Results:

    • Peanut agglutinin (PNA) and Ulex europaeus (UEA-I) showed weak apical epithelial binding in proliferative/secretory phases, becoming strongly positive in pregnancy.
    • Wheat germ agglutinin (WGA) and Ricinus communis (RCA-I) exhibited increased binding to glandular epithelium from the proliferative to secretory phases.
    • Concanavalin A (Con A) demonstrated strong affinity for decidual cells.

    Conclusions:

    • Lectin binding patterns in the endometrium vary significantly with the menstrual cycle and pregnancy.
    • These changes suggest dynamic alterations in endometrial glycoconjugates during reproductive processes.
    • Lectin analysis provides a valuable tool for understanding endometrial differentiation and receptivity.