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Benefits of a comprehensive care model in patients with heart failure and preserved ejection fraction: The UMIPIC
J M Cerqueiro-González1, Á González-Franco2, S Carrascosa-García3
1Servicio de Medicina Interna, Hospital Universitario Lucus Augusti, Lugo, Spain.
Insights
A comprehensive continuous care program (UMIPIC program) significantly reduced hospital admissions and mortality in heart failure with preserved ejection fraction (HFpEF) patients. This approach offers a vital benefit for managing this high-risk population.
Area of Science:
- Cardiology and Internal Medicine
- Clinical Trial Research
- Patient Management Strategies
Background:
- Heart failure with preserved ejection fraction (HFpEF) affects older patients with multiple comorbidities.
- HFpEF patients often lack effective therapeutic options and face high risks of hospitalization and mortality.
- This study investigates the impact of a specialized care program on HFpEF outcomes.
Purpose of the Study:
- To evaluate the effectiveness of the comprehensive continuous care program (UMIPIC program) in patients with HFpEF.
- To assess the program's impact on reducing hospital admissions and mortality rates.
Main Methods:
- Prospective analysis of 2401 HFpEF patients from the RICA registry.
- Comparison between the UMIPIC program group (n: 1011) and conventional care group (RICA, n: 1390).
- Propensity score matching (753 patients per group) to ensure comparability; 12-month follow-up for admissions and mortality.
Main Results:
- The UMIPIC group showed significantly lower HF admission rates (19.2% vs. 36.5%; HR=0.56) compared to the RICA group.
- Mortality was substantially reduced in the UMIPIC group (12.6% vs. 28%; HR=0.40).
- No significant difference in non-HF related hospitalizations was observed between the groups.
Conclusions:
- The UMIPIC program, a comprehensive continuous care model, effectively reduces hospital admissions for HFpEF patients.
- This program also significantly lowers mortality rates in HFpEF patients with high comorbidity.
- Continuous care is a beneficial strategy for managing high-risk HFpEF populations.
Background:
Patients with heart failure (HF) and preserved ejection fraction (HFpEF), in contrast to those with reduced ejection fraction, are older, have more comorbidities, and are not candidates for effective therapeutic measures. Therefore, they are at high risk for hospital admission and mortality. This study evaluated the benefit of a comprehensive continuous care program (UMIPIC program) in patients with HFpEF.
Methods:
We prospectively analyzed data on 2401 patients with HFpEF attended to in internal medicine departments who form part of the RICA registry. They were divided into 2 groups: one was followed-up on in the UMIPIC program (UMIPIC group, n: 1011) and another received conventional care (RICA group, n: 1390). A total of 753 patients in each group were selected by propensity score matching and admissions and mortality were assessed during 12 months of follow-up after an episode of hospitalization due to HF.
Results:
Compared to the RICA group, the UMIPIC group had a lower rate of HF admissions (19.2% versus 36.5%, respectively; hazard ratio [HR] = 0.56; 95% confidence interval [CI]: 0.45-0.68; p < 0.001) and mortality (12.6% versus 28%, respectively; HR = 0.40; 95% CI: 0.31-0.51; p < 0.001). There were no differences in hospitalizations for non-HF causes.
Conclusions:
Implementation of the UMIPIC program, which is based on comprehensive continuous care, for patients with HFpEF and a high degree of comorbidity reduces both admissions and mortality in the first year of follow-up.
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