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A Case of Anti-SAE1 Dermatomyositis
Max de Vries1, Marco W J Schreurs2, Els J M Ahsmann3
1Department of Internal Medicine, Groene Hart Hospital, Bleulandweg 10 2803 HH, Gouda, Netherlands.
Introduction:
Anti-SAE1 antibodies have a low prevalence in dermatomyositis patients. Case Description. A 61-year-old woman presented with progressive shortness of breath, arthralgia, heliotrope rash, Gottron's papules, and erythematous rash. She had an interstitial lung disease (ILD) with a significant decrease in lung function. There was no muscle involvement. Immunological laboratory test results showed strongly positive anti-SAE1 antibodies. Glucocorticoid treatment resulted in remission of dermatomyositis.
Conclusion:
Anti-SAE antibodies in dermatomyositis patients are closely linked to unique clinical features.
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