A multicenter retrospective study of transurethral prostate split for benign prostate hyperplasia

Area of Science:

• Urology
• Surgical Innovation
• Patient Outcomes

Background:

• Benign prostatic hyperplasia (BPH) is a common condition in aging men.
• Transurethral split of the prostate (TUSP) is an established treatment for BPH.
• Optimal patient selection criteria for TUSP remain under investigation.

Purpose of the Study:

• To compare the efficacy of TUSP in BPH patients with varying prostate volumes.
• To evaluate the impact of patient age on TUSP outcomes.
• To identify potential factors influencing TUSP treatment success.

Main Methods:

• Multicenter retrospective study involving 439 BPH patients.
• Patients categorized by prostate volume (≤50 mL vs. >50 mL) and age (≤70 years vs. >70 years).
• Comparison of baseline characteristics, perioperative data, and 12-month follow-up outcomes (IPSS, QoL, PVR, Qmax).

Main Results:

• TUSP significantly improved IPSS, QoL, PVR, and Qmax at 12 months.
• Smaller prostate volumes were associated with lower intraoperative blood loss and fewer postoperative urgency/incontinence events.
• Younger patients showed greater variability in PVR and Qmax but less in QoL compared to older patients.

Conclusions:

• TUSP is a safe and effective BPH treatment across different patient groups.
• Prostate volume and patient age influence TUSP outcomes, particularly in the short term.
• Clinical decisions for TUSP may benefit from considering both prostate size and patient age.