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Complications of Autoimmune Hemolytic Anemia

Surbhi Shah1, Leslie Padrnos1

  • 1Division of Hematology and Medical Oncology, Mayo Clinic Arizona, 5881 E. Mayo Boulevard, Phoenix, AZ 85054, USA.

Hematology/Oncology Clinics of North America
|March 14, 2022
PubMed

Autoimmune hemolytic anemia (AHIA) is the group of acquired autoimmune conditions resulting from the development of autologous antibodies directed against autologous red blood cell antigens resulting in red cell lysis. Beyond the presence, severity, and duration of hemolysis which can lead to symptomatic anemia, additional complications at presentation and during treatment require a high degree of clinical vigilance. These include among others cutaneous, thrombotic, renal disorders, and infectious disorders. Complications can be due to the presence of the pathologic antibody itself, the process of hemolysis, or attributed to treatment. Comprehensive management of AIHA requires awareness and assessment of complications at diagnosis, during, and following treatment.

Keywords:
Autoimmune hemolytic anemiaCOVID-19Immunosuppressive therapyVenous thromboembolism

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