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HPV Vaccination Status and Resolution of Warts in Pediatric Patients
Anuk Burli1, Sarah Hancock1, Yu Tina Zhao1
1Department of Dermatology, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States.
Insights
Human papillomavirus (HPV) vaccination status did not affect wart resolution in pediatric patients. However, vaccinated children required more treatment visits, possibly due to increased healthcare compliance.
Area of Science:
- Dermatology
- Pediatrics
- Immunology
Background:
- Warts are common in children and caused by human papillomavirus (HPV).
- Limited research exists on HPV vaccination's impact on pediatric wart treatment outcomes.
Purpose of the Study:
- To investigate the relationship between HPV vaccination status and the resolution of warts in pediatric patients.
Main Methods:
- Retrospective chart review.
- Analysis of the correlation between HPV vaccination status and wart treatment response.
Main Results:
- No significant relationship was found between HPV vaccination status and wart resolution (p = 0.797).
- A significant positive correlation was observed between HPV vaccination and an increased number of treatment visits (r = 0.180, P = 0.024).
Conclusions:
- HPV vaccination status did not significantly correlate with wart resolution in pediatric patients.
- Vaccinated patients showed a trend towards more treatment visits, potentially linked to higher healthcare compliance.
Background:
Warts are a common dermatologic complaint with an increased incidence within the pediatric population. Warts are caused by multiple strains of the human papillomavirus (HPV). There is little research on how a patient's HPV immunization status affects the response to treatment of warts in pediatric patients.
Aims:
The purpose of this study is to investigate the relationship between HPV vaccination status and wart resolution.
Materials And Methods:
This is a retrospective chart review that investigates the relationship between response to routine treatment of warts and a subject's HPV vaccination status.
Results:
There was no significant relationship found between HPV vaccination status and resolution of warts (p = 0.797). However, there was a significant positive correlation between having the HPV vaccine and number of visits for the treatment of warts (r = 0.180, P = 0.024).
Conclusion:
This study did not show a significant correlation between HPV vaccination status and wart resolution, although it demonstrated a significant positive relationship between those immunized with the HPV vaccine and an increased number of treatment visits. Possible explanations for this unexpected correlation include the variation in HPV vaccine formulation, vaccination status, and frequency of office visits, since vaccinated patients are more likely to be compliant with office visits.
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