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Warning Signs of Potential Black Swan Outbreaks in Infectious Disease
Nileena Velappan1, Katie Davis-Anderson1, Alina Deshpande1
1Biosecurity and Public Health, Bioscience Division, Los Alamos National Laboratory, Los Alamos, NM, United States.
Identifying warning signs for infectious disease black swan events is possible. Analyzing historical outbreak data reveals common features that can alert authorities to impending large-scale epidemics, improving response efforts.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health Analytics
Background:
- Black swan events in infectious diseases are rare, large-scale outbreaks with devastating consequences.
- Predicting these events is challenging, but identifying early warning signs following an outbreak's initiation may be feasible.
- Common features across pathogen, environment, and host factors could characterize these high-impact events.
Purpose of the Study:
- To investigate potential common features of infectious disease black swan events.
- To explore the utility of data analytics in identifying early warning signs for large outbreaks.
- To assess if these events are linked solely to the initial introduction of a pathogen.
Main Methods:
- Utilized Los Alamos National Laboratory's Analytics for Investigation of Disease Outbreaks tool.
- Analyzed historical outbreak data and anomalous events for 32 different infectious diseases.
- Conducted a meta-analysis of large outbreaks across multiple infectious disease categories.
Main Results:
- Potential black swan events have occurred in the majority of analyzed infectious diseases in the last 20-30 years.
- These significant outbreaks were not solely attributable to the initial introduction of the disease to a susceptible population.
- Broad data analysis across various infectious diseases provided insights not obtainable from single-agent studies.
Conclusions:
- Common epidemiological features may characterize infectious disease black swan events.
- Data analytics tools can be developed to provide early warnings for impending large outbreaks.
- Such tools can complement traditional epidemiological modeling for improved forecasting and resource allocation.
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